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Of course, if the tube has partially clotted (poor mixing), or the patient is heparinized from dialysis, or the specimen is drawn downstream from an intravenous fluid site, or the phlebotomist did not fill the tube completely or mix it properly, there s also likely to be a falsely long inr.
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Any that s left-over stimulates the production of more platelets.
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COAGULATION DISORDERS Ed Friedlander, M.D., Pathologist [email protected] No texting or chat messages, please. Ordinary e
Hereditary deficiency of antithrombin iii is quite common.
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The activating of the clotting factors, which takes minutes, is called secondary hemostasis.
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* hiv-positive patients often make a unique antibody against gpiiia that fragments platelets without complement involvement.
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Platelet problems are often heralded by petechiae on the skin and mucosal surfaces.
88: 82, 1995), * ticlopidine (as after coronary stenting, jama 281: 806, 1999) and others.
If platelets are being destroyed peripherally, you will see many, young megakaryocytes with hypo-segmented nuclei.
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Thromboelastrography: blood is rotated in a cup and a sensor measures how fast it clots and how tough the clot is.
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) * tomorrow s high-tech blood bank may contain equipment that generates platelets from cell cultures, without a donor: blood 121: 3319, 2013.
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Tip: get a functional, rather than an immune-based, assay for proteins c, s, at-iii, etc.